22 days in Italy Itinerary

22 days in Italy Itinerary

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Route & dates

22 days in Italy Itinerary

Start: Dusseldorf
Fly:  4 h 30 min
1
Venice
— 2 nights
Fly:  3 h 15 min
2
Rome
— 4 nights
Train:  1 h 45 min
3
Salerno
— 3 nights
Ferry:  1 h 30 min
4
Positano
— 3 nights
Drive:  4 h 45 min
5
Assisi
— 3 nights
Drive:  2 h 15 min
6
Florence
— 3 nights
Train:  1 h 45 min
7
Verona
— 2 nights
Train:  1 h 15 min
8
Milan
— 1 night
Fly:  4 h 15 min
End: Dusseldorf

2
nights
Venice

Venice ©
Virtually unchanged for the last six centuries, Venice is actually a group of islands made famous by a series of canals, bridges, monuments, piazzas, and narrow pedestrian lanes.
Venice is known for historic sites, museums, and nature. Your plan includes some of its best attractions: explore the activities along Canal Grande, browse the exhibits of Doge's Palace, appreciate the history behind Punta della Dogana, and get to know the fascinating history of Piazza San Marco.

To find where to stay, more things to do, maps, and more tourist information, use the Venice trip maker tool.

Dusseldorf, Germany to Venice is an approximately 4.5- hour flight. You can also do a combination of train and flight; or drive. Expect a bit warmer temperatures when traveling from Dusseldorf in September; daily highs in Venice reach 29°C and lows reach 17°C. Wrap up your sightseeing on the 18th (Fri) early enough to travel to Rome.

Things to do in Venice

Historic Sites Museums Parks
Find places to stay Sep 16 — 18:
Highlights from your plan
Canal Grande ©
Canal Grande
Basilica di San Marco
Basilica di San Marco
Piazza San Marco ©
Piazza San Marco

4
nights
Rome

Rome ©
Aptly nicknamed the Eternal City, Rome is the birthplace of the Roman Empire, one of the world's greatest civilizations ever.
Rome is known for historic sites, nightlife, and museums. Your plan includes some of its best attractions: contemplate the long history of Colosseum, make a trip to Spanish Steps, ponder the design of Trevi Fountain, and admire the masterpieces at Vatican Museums.

To see other places to visit, more things to do, photos, and other tourist information, refer to the Rome day trip planning site.

You can fly from Venice to Rome in 3.5 hours. Other options are to take a train; or drive. In September, plan for daily highs up to 32°C, and evening lows to 18°C. Finish your sightseeing early on the 22nd (Tue) to allow enough time to take a train to Salerno.

Things to do in Rome

Historic Sites Museums Neighborhoods

Side Trip

Vatican City
Find places to stay Sep 18 — 22:
Highlights from your plan
Colosseum ©
Colosseum
Pantheon ©
Pantheon
St. Peter's Basilica ©
St. Peter's Basilica

3
nights
Salerno

Salerno ©
While often overshadowed by the Amalfi Coast's array of quaint villages, Salerno has become one of the region's main areas for culture and entertainment, while remaining relatively unmarked by tourism.
Explore the numerous day-trip ideas around Salerno: Monte Finestra (in Tramonti), Ravello (Cappella Sant'Angelo all'Ospedale, Ceramiche Cosmolena di Margherita di Palma, &more) and Castello di San Nicola de Thoro-Plano (in Maiori). There's much more to do: delve into the distant past at Pompeii Archaeological Park, enjoy the sand and surf at Spiaggia di castiglione, head outdoors with Cilento, and tour the pleasant surroundings at Marina Di Vietri.

To see reviews, ratings, traveler tips, and other tourist information, use the Salerno route maker tool.

You can take a train from Rome to Salerno in 2 hours. Alternatively, you can drive; or take a bus. Expect somewhat warmer evenings in Salerno when traveling from Rome in September, with lows around 24°C. Cap off your sightseeing on the 25th (Fri) early enough to catch the ferry to Positano.

Things to do in Salerno

Outdoors Beaches Parks

Side Trips

Ravello, Vietri sul Mare, Monte Finestra, Basilica of Saint Trofimena, Pompeii Archaeological Park
Find places to stay Sep 22 — 25:
Highlights from your plan
Pompeii Archaeological Park ©
Pompeii Archaeological Park
Spiaggia di castiglione ©
Spiaggia di castiglione

3
nights
Positano

Positano ©
Often referred to as the gem of the Amalfi Coast, Positano remains one of southern Italy's most sought-after vacation locales, thanks to its hillside location and picturesque, pastel buildings.
Change things up with these side-trips from Positano: Ravello (Ceramiche d'Arte Carmela, Duomo di Ravello, &more) and Duomo di Sant'Andrea (in Amalfi). There's lots more to do: kick back and relax at Fornillo, take in the spiritual surroundings of Cloister del Paradiso, get outside with I Suoni degli Dei - Pelagos, and stop by Nana' Positano.

For maps, reviews, more things to do, and other tourist information, read our Positano visit planner.

You can ride a ferry from Salerno to Positano in 1.5 hours. Other options are to do a combination of train and taxi; or drive. September in Positano sees daily highs of 31°C and lows of 23°C at night. Finish your sightseeing early on the 28th (Mon) so you can drive to Assisi.

Things to do in Positano

Outdoors Parks Historic Sites

Side Trips

Ravello, Praiano, Amalfi
Find places to stay Sep 25 — 28:
Highlights from your plan
Fornillo ©
Fornillo
Boat Tours & Water Sports
Il Sentiero Degli Dei ©
Il Sentiero Degli Dei

3
nights
Assisi

Assisi ©
Rich in culture and religious tradition, Assisi is known as the birthplace of St.
Venture out of the city with trips to Montioni Frantoio e Cantina (in Montefalco) and Galleria Nazionale dell'Umbria (in Perugia). The adventure continues: pause for some serene contemplation at Basilica Papale e Sacro Convento di San Francesco d'Assisi, make a trip to Eremo delle Carceri, explore the historical opulence of Rocca Maggiore, and walk around Mount Subasio.

To find ratings, traveler tips, and more tourist information, you can read our Assisi trip planner.

Getting from Positano to Assisi by car takes about 5 hours. Other options: do a combination of bus, subway, and train; or take a bus. Plan for little chillier nights when traveling from Positano in September since evenings lows in Assisi dip to 16°C. Finish your sightseeing early on the 1st (Thu) so you can drive to Florence.

Things to do in Assisi

Wineries Historic Sites Museums

Side Trips

Montioni Frantoio e Cantina, Galleria Nazionale dell'Umbria
Find places to stay Sep 28 — Oct 1:
Highlights from your plan
Tili Vini Societa Agricola ©
Tili Vini Societa Agricola
Eremo delle Carceri ©
Eremo delle Carceri

3
nights
Florence

Florence ©
Considered a cultural, artistic, and architectural jewel of Italy, Florence is the birthplace of the Italian Renaissance.
Florence is known for museums, historic sites, and shopping. Your plan includes some of its best attractions: admire the masterpieces at Academy Of Florence Art Gallery, take in the architecture and atmosphere at Basilica of Santa Croce, appreciate the extensive heritage of Piazza del Duomo, and take in the spiritual surroundings of Cathedral of Santa Maria del Fiore.

For maps, other places to visit, and other tourist information, read Florence trip maker app.

You can drive from Assisi to Florence in 2.5 hours. Another option is to take a train. In October, daily temperatures in Florence can reach 25°C, while at night they dip to 14°C. Finish your sightseeing early on the 4th (Sun) to allow enough time to take a train to Verona.

Things to do in Florence

Historic Sites Museums Shopping
Find places to stay Oct 1 — 4:
Highlights from your plan
M.G. Design ©
M.G. Design
Academy Of Florence Art Gallery ©
Academy Of Florence Art Gallery
Piazzale Michelangelo ©
Piazzale Michelangelo

2
nights
Verona

Verona ©
The famous setting for Shakespeare's star-crossed lovers, Romeo and Juliet, Verona is one of northern Italy's main tourist destinations, largely owing to its incredibly rich artistic heritage.
Kick off your visit on the 5th (Mon): make a trip to Liston, see the grandeur of opera at Arena di Verona, steep yourself in history at Piazza delle Erbe, then take in panoramic vistas at Torre dei Lamberti, then see the interesting displays at Casa di Giulietta, and finally contemplate in the serene atmosphere at Basilica di San Zeno Maggiore. Keep things going the next day: take in the architecture and atmosphere at San Fermo Maggiore, Verona, take in the architecture and atmosphere at chiesa di San Lorenzo - Verona, then take a stroll through Quinzano, and finally let the river carry you with a rafting and tubing tour.

For more things to do, photos, maps, and tourist information, go to the Verona online road trip planner.

Traveling by train from Florence to Verona takes 2 hours. Alternatively, you can drive; or take a bus. When traveling from Florence in October, plan for slightly colder days and about the same nights in Verona: temperatures range from 22°C by day to 11°C at night. Finish your sightseeing early on the 6th (Tue) to allow enough time to take a train to Milan.

Things to do in Verona

Historic Sites Neighborhoods Tours
Find places to stay Oct 4 — 6:
Highlights from your plan
Arena di Verona ©
Arena di Verona
Piazza delle Erbe ©
Piazza delle Erbe
Basilica di San Zeno Maggiore ©
Basilica di San Zeno Maggiore

1
night
Milan

Milan ©
In many ways the most modern of Italian cities, Milan is a busy, elegant metropolis with an impressive list of grand palaces, fine churches, and important museums.
Start off your visit on the 7th (Wed): explore the historical opulence of Castello Sforzesco, pause for some serene contemplation at Duomo di Milano, and then admire the landmark architecture of Galleria Vittorio Emanuele II.

To find where to stay, other places to visit, traveler tips, and more tourist information, you can read our Milan trip itinerary maker tool.

Traveling by train from Verona to Milan takes 1.5 hours. Alternatively, you can drive. Expect a daytime high around 21°C in October, and nighttime lows around 13°C. Wrap up your sightseeing on the 7th (Wed) to allow time to travel back home.

Things to do in Milan

Historic Sites Shopping
Find places to stay Oct 6 — 7:
Highlights from your plan
Duomo di Milano ©
Duomo di Milano
Galleria Vittorio Emanuele II ©
Galleria Vittorio Emanuele II
Castello Sforzesco ©
Castello Sforzesco

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